Found 82 matching trials
Safety, Tolerability and Efficacy of PfSPZ Vaccine Against Heterologous CHMI in US Malaria naïve Adults PHASE1 This is a randomized, double blind, placebo-controlled, single site, trial ...
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Fred Hutchinson Cancer Research Center
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Safety and Immunogenicity in Age De-Escalation of PfSPZ Vaccine in Tanzanian Adults, Children, and Infants PHASE1 The present trial will evaluate safety and tolerability as well as the vacc...
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Bagamoyo Research and Training center of the Ifakara Health Institute
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Durability of Protection After Single Immunisation With GA2 Sporozoites (CoGA-Rechallenge) PHASE1 This study will assess the durability of protection of a single immunisatio...
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Multiple Locations
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PfSPZ Challenge in Healthy Malaria-Naïve Adults in the United States PHASE1 This phase I trial of the replication-intact PfSPZ Challenge vaccine given ...
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Kaiser Permanente Washington Health Research Institute - Vaccines and Infectious Diseases
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Evaluate the Infectivity Equivalence of Current and New Lots of Plasmodium Falciparum Strain NF54 PHASE1 Objectives:
Primary:
• To characterize the infectivity of the new lot of ...
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Walter Reed Army Institute of Research
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Study to Evaluate Safety, Immunogenicity and Efficacy of PfSPZ Vaccine in HIV Negative and HIV Positive Tanzanian Adults PHASE1 This is a randomized, double-blind, placebo-controlled trial to evaluate sa...
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Bagamoyo Research and Training Center of the Ifakara Health Institute
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VAC063C: A Study to Assess Repeat Blood-stage P. Falciparum Infection NA This is a clinical study to assess the safety of primary, secondary and ter...
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CCVTM, University of Oxford, Churchill Hospital
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A Safety and Efficacy Study of Concomitant Administration of ChAd63/MVA ME-TRAP + RTS,S PHASE1 The purpose of this study is to assess two types of new malaria vaccines in...
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NIHR WTCRF, University Hospital Southampton NHS Foundation Trust
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Oral Doxycycline for the Prevention of Syphilis in Men Who Have Sex with Men (DaDHS) PHASE4 Syphilis is a sexually transmitted infection (STI) disproportionately affec...
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British Columbia Centre for Disease Control
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Dose Escalation, Randomized Controlled Trial to Evaluate the Safety, Immunogenicity and Efficacy of Intravenously Administered Attenuated Plasmodium Falciparum Sporozoite Vaccine (PfSPZ Vaccine) in Tanzanian Adults PHASE1 This trial will evaluate whether relatively non-immune populations in endem...
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Bagamoyo Research and Training Center, Ifakara Health Institute, Kingani Estate, PO Box 74
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